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The history of psychedelic substance use, modern research efforts, and their potential clinical applications addressing current treatment resistant mental health disorders evolved through an intriguing and complexly interwoven story linking ancient cultures, modern discovery, pop cultural movements, national and international politics, and well-intentioned laws with unintended consequences. In the context of this history, this commentary discusses the 21st century resurgence of psychedelic drug assisted psychotherapeutic research, the challenges imposed by the United States Controlled Substance Act (US CSA), and the potential for development of medicinal products for the treatment of persisting mental health disorders.
The unrelenting persistence of behavioral disorders, for which those who are afflicted and refractory to current evidenced based therapies, reveal a powerful incentivizing force for advancing new medicinally assisted psychotherapeutic treatments. On the other hand, we enter the 21st century humbled by the daunting challenge of developing medicines for central nervous system (CNS) disorders in response to the failure of so many seemingly promising medicines that emerged from years of clinical trials, billions of US dollars invested, with benefit to risk profiles which at the time, were acceptable to regulatory agencies in the US and globally (Hyman, 2012; Pangalos et al., 2007; Pankevich et al., 2014). With these considerations in mind, the present commentary is not postured as advocacy for a simple or certain solution to the challenges posed by mental health disorders or “brain diseases.” Nonetheless, it suggests that pressing public health challenges involving behavioral disorders may be addressed in part by recent advances in neuropharmacology, on the effects, mechanisms of action, and potential clinical applications of psychedelic drugs discussed in this special issue of Neuropharmacology. Together, these advances support our conclusion that increased scientific investigation of psychedelic substances for potential clinical application merits serious consideration among the many other efforts that are vigorously being pursued to address mental health illnesses that continue to be so pervasive in the United States and globally.
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Are Psychedelics Mushroom Legal In Utah? Utah’s laws are particularly tough on psychedelic drugs. Possessing LSD, MDMA, or magic mushrooms can lead to up to 10 years in prison or $5000 in fines. Ketamine, however, carries lesser penalties as it is legal for medical use. This article will explain to you the most important laws …
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Are Psychedelics Mushrooms Legal In Nebraska? The topic of marijuana legalization seems to take over the news, but it’s not the only controlled substance that’s teetering on legalization due to its massive health benefits. Psychedelics like magic mushrooms and MDMA could be used for many health issues if they weren’t Schedule I Drugs. Several US …
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Are Psychedelics Mushrooms legal In Brunswick? Psychedelics are illegal in New Brunswick, Canada, and even though authorities may not prosecute the user, fines and penalties remain in force. Still, citizens can apply for medical exemptions. Moreover, the federal government has received petitions to decriminalize controlled substances from other provinces. This article will discuss these substances and …
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Are Psychedelics Legal In new Jersey? Most psychedelics are illegal in the state of New Jersey — however, as recently as February of 2021, magic mushroom possession penalties (and a few other natural psychedelics) were significantly reduced. Here, we’ll explore the current laws and regulations for magic mushrooms, LSD, ketamine, MDMA, and more in the …
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Are Psychedelics mushrooms Legal in Mexico? Mexico’s laws are tough to navigate and understand, and if you don’t speak Spanish, it will be a near-impossible task. In addition, many different sanctions overlap, and the internet is filled with outdated information. So, if you’re feeling lost, you’ve come to the right place — we’ve collected everything …
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Are Psychedelics Legal in South Carolina? Psilocybin mushrooms contain a natural hallucinogenic compound called psilocybin. Even though psilocybin is federally classified as a Schedule I substance, researchers have suggested a reclassification. Surprisingly, some states have taken action and are in the process of decriminalizing psilocybin along with a few other psychedelic compounds. Here’s where South Carolina …
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Are Psychedelics Mushroom Drugs Legal In Michigan? The city of Ann Arbor, Michigan is the latest city to decriminalize the use of natural psychedelics — including magic mushrooms, peyote, San Pedro, ayahuasca, iboga, and more. Here, we’ll explore the current state of psychedelic drug laws and decriminalization in Michigan, both within Ann Arbor and the rest of …
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